2024 · bioinformatics
NGS Secondary Analysis Pipeline
A pipeline for the UCLA Pellegrini Lab that turns canine whole-genome sequencing data into labeled VCFs, tuned for large indels.
what i built
- Built an NGS secondary-analysis pipeline in Linux to process canine whole-genome sequencing data into labeled VCF outputs.
- Tuned parameters with Prof. Pellegrini to improve indel detection sensitivity, reaching a 95% large-indel identification rate.
- Adapted the script to the lab’s needs as part of broader research that synthesized findings from 400+ WGS studies to prioritize disease-associated genes.